The effect of the AP technology on environmental surface and floor aerobic bacteria, fungi, and Methicillin-resistant Staphylococcus aureus (MRSA) and airborne aerobic bacteria and fungi was designed as a prospective controlled experimental study, using pre-activation environmental samples as the baseline to compare to post-activation samples in the intervention center. Statistically significant reductions of greater than 92% were reported for all surface and floor samples after AP technology activation. Air testing showed reductions of aerobic bacteria and fungi by 87% and 36%, respectively, but were not statistically significant, likely due to small sample size (n=10). The intervention center performed 68% better than the control centers with a 79% reduction in staff COVID19 cases compared to the same matched time period one year prior. The incidence of resident COVID19 cases was reduced 94% in the intervention center while the control centers experienced a 46% increase compared to the matched time period one year prior.